Loss of Anti-Microbial Peptides as a Mechanism for Age-Related Changes in Gut Microbiome Composition

This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression promotes increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes.

Source: Fight Aging! - March 27, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs