Association Between Quantitative and Qualitative Imaging Biomarkers and Geographic Atrophy Growth Rate

Advanced age-related macular degeneration is one of the leading causes of blindness in the United States and worldwide.1 The advanced non-neovascular stage is characterized by the presence of geographic atrophy (GA), or complete retinal pigment epithelium and outer retina atrophy (cRORA), defined by atrophy of the retinal pigment epithelium (RPE) and retinal photoreceptors in the macula.2 As GA enlarges over time this leads to an irreversible decline in visual function and patient-reported outcomes.

Source: American Journal of Ophthalmology - March 27, 2024 Category: Opthalmology Authors: Talisa E. de Carlo Forest, Zafar Gill, Andres Lisker-Cervantes, Ramya Gnanaraj, Nathan Grove, Jennifer L. Patnaik, Anne M. Lynch, Alan G. Palestine, Marc Mathias, Niranjan Manoharan, Naresh Mandava Source Type: research