Recurrent miscarriage and low-titer antiphospholipid antibodies

ConclusionNoteworthy distinctions in laboratory parameters were identified between the low-titer and medium-high titer groups. However, when appropriately treated, the fetal-maternal outcomes were comparable in both groups. Timely intervention by clinicians is imperative to enhance pregnancy outcomes in patients experiencing recurrent miscarriage with low levels of aPL.Key Points•This study challenges the conventional belief that only the higher antiphospholipid antibodies (aPL) titers directly correlated with worse pregnancy outcomes, which emphasized the importance of patients with low titer positive aPL-positive RM.•The results underscore the need for timely intervention in women with low titer aPL-positive RM, as it leads to favorable maternal –fetal outcomes.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research