Association of lipid-modifying therapy with risk of obstructive sleep apnea: A drug-target mendelian randomization study

CONCLUSIONS: The present study presented genetic evidence supporting the association of LDL-C-lowering therapy by CETP inhibition with reduced risk of OSA. These findings provided novel insights into the role of lipid management in patients with OSA and encouraged further clinical validations and mechanistic investigations.PMID:38521370 | DOI:10.1016/j.taap.2024.116909

Source: Toxicology and Applied Pharmacology - March 23, 2024 Category: Toxicology Authors: Juanjuan Zou Shengnan Qi Xiaojing Sun Yijing Zhang Yan Wang Yanzhong Li Ze-Hua Zhao Dapeng Lei Source Type: research