Ocular pharmacological and biochemical profiles of 6-thioguanine: a drug repurposing study

Conclusion:6TG evidenced a marked anti-angiogenic activity in HUVECs exposed to high glucose and in mice with DR. This seems to be mediated by MC1R and MC5R retinal receptors.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research