Effect of Annexin A2 on prognosis and sensitivity to immune checkpoint plus tyrosine kinase inhibition in metastatic renal cell carcinoma

ConclusionsUpregulated ANXA2 was associated with poor PFS and therapeutic resistance in RCC treated by IO  + TKI therapy, and related with T cell exhaustion. The integrated RF score could stratify patients who would benefit from IO + TKI therapy.
Source: Hormones and Cancer - Category: Cancer & Oncology Source Type: research