Human recombinant relaxin-2 (serelaxin) regulates the proteome, lipidome, lipid metabolism and inflammatory profile of rat visceral adipose tissue

In conclusion, our results highlight the regulatory role of serelaxin in the VAT proteome and lipidome, lipolytic function, and inflammatory profile, suggesting the implication of several mechanisms supporting the potential benefit of serelaxin for the prevention of obesity and metabolic disorders.PMID:38518995 | DOI:10.1016/j.bcp.2024.116157

Source: Biochemical Pharmacology - March 22, 2024 Category: Drugs & Pharmacology Authors: Alana Arag ón-Herrera Sandra Feij óo-Bandín Xocas V ázquez-Abuín Laura Anido-Varela Sandra Mora ña-Fernández Susana B Bravo Estefan ía Tarazón Esther Rosell ó-Lletí Manuel Portol és Javier Garc ía-Seara Jos é Seijas Diego Rodr íguez-Penas D Source Type: research