Effect of tofacitinib on the phenotype and activity of Caco ‑2 cells in a model of inflammatory bowel disease

In conclusion, the inhibitory effects of tofacitinib on oxidative stress, as well as its anti-apoptotic and regenerative effects, provide important information regarding the positive effect of tofacitinib on Caco-2 cells, and therefore constitute potential information about the beneficial effect of the evaluated drug in UC.PMID:38476894 | PMC:PMC10928998 | DOI:10.3892/etm.2024.12440
Source: Experimental and Therapeutic Medicine - Category: General Medicine Authors: Source Type: research