Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19

CONCLUSIONS: Taken together, these observations further elucidate the pathological mechanisms that underlie immune dysfunction and coagulation abnormalities in COVID-19, contributing to our growing understanding of SARS-CoV-2 infections that could also be leveraged to develop novel diagnostic and therapeutic strategies.PMID:38511328 | DOI:10.1161/ATVBAHA.122.318721

Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 21, 2024 Category: Cardiology Authors: Sascha N Goonewardena Qinzhong Chen Ashley M Tate Olga G Grushko Dilna Damodaran Pennelope Blakely Salim S Hayek David J Pinsky Robert S Rosenson Source Type: research