The Alberta Infant Motor Scale as an Outcomes Measure of Gross Motor Abilities after Early Complex Cardiac Surgery

AbstractTo address the research hypothesis that the Alberta Infant Motor Scale (AIMS) completed following complex cardiac surgery (CCS) is a useful outcomes measure this study determined: (1) AIMS scores at age 8  months after CCS; (2) predictive validity of AIMS at 8 months for Bayley Scales of Infant and Toddler Development-III Gross Motor-scaled scores (GMSS) and diagnosis of cerebral palsy (CP) at 21 months; and (3) predictive demographic and surgical variables of AIMS scores. A prospective cohort stu dy of 250/271 (92.3%) surviving children from Northern Alberta (born 2009–2020) who had CCS at age <  6 months determined AIMS scores at age mean (SD) 8.6 (2.4) and the GMSS at 21.9 (3.8) months. Gross motor delay was defined as AIMS <  5th percentile and GMSS as <  4 (-2SD). Predictions using multiple logistic regressions were expressed as Odds Ratios (OR) and 95% Confidence Interval (CI). Of children, 100/250 (40%) had AIMS <  5th predicting GMSS <  4 (n = 43); sensitivity, specificity, positive, and negative predictive values were 88%, 71%, 40%, and 97%. Hospitalization days were independently associated with AIMS <  5th, OR 1.02 (95% CI 1.007, 1.032;p = 0.005). Excluding hospital days, ventilation days independently predicted AIMS <  5th, OR 1.08 (95% CI 1.038, 1.125,p <  0.001. Gross motor delay determine by AIMS scores of <  5th percentile occurred in 40% of survivors with good prediction of c...
Source: Mammalian Genome - Category: Genetics & Stem Cells Source Type: research