The Effect of Polymorphisms and Other Biomarkers on Infliximab Exposure in Paediatric Inflammatory Bowel Disease: Development of a Population Pharmacokinetic Model

CONCLUSIONS: A popPK model utilising weight, albumin, FC, ESR, and the SNP rs1048610 accurately predicted infliximab trough concentrations in children with IBD.PMID:38507036 | DOI:10.1007/s40272-024-00621-1

Source: Paediatric Drugs - March 20, 2024 Category: Pediatrics Authors: Susana Clemente-Bautista I ñaki F Trocóniz Óscar Segarra-Cantón Sara Salvador-Mar ín Carlos J Parram ón-Teixidó Marina Álvarez-Beltrán Lu ís A López-Fernández Helena Colom Maria J Caba ñas-Poy Maria Q Gorgas-Torner Marta Miarons Source Type: research