Effective dose of intranasal remimazolam for preoperative sedation in preschool children: a dose-finding study using Dixon ’s up-and-down method

Conclusion:Intranasal remimazolam is feasible for preschool children with a short onset time. For successful pre-induction sedation, the ED50 and ED95 of intranasal remimazolam were 0.65 and 0.78 mg/kg, respectively.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research