Examining the causal relationship between circulating immune cells and the susceptibility to osteomyelitis: A Mendelian randomization study

CONCLUSION: Through our MR analysis, we have provided evidence supporting a causal relationship between genetic predisposition to higher circulating immune cell counts and an increased risk of osteomyelitis. Specifically, our findings highlight the association between elevated CD8+ T cell counts and a heightened susceptibility to osteomyelitis. These results offer valuable insights for the future exploration of immunotherapy approaches in the management of osteomyelitis.PMID:38492335 | DOI:10.1016/j.intimp.2024.111815
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Source Type: research