Double Balloon Catheter-Mediated Transarterial Chemotherapy Delivery in a Swine Model: A Mechanism Recruiting the Vasa Vasorum for Localized Therapies

This report examines the potential mechanism of localized drug delivery via trans-arterial micro perfusion (TAMP) using a proprietary adjustable double-balloon occlusion catheter in a porcine model. Adult Yorkshire swine (N=21) were used in IACUC-approved protocols. The RC-120 catheter was positioned into visceral, femoral, and pulmonary arteries with infusion of methylene blue dye, gemcitabine, or gold nanoparticles.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Laboratory Investigation Source Type: research