Double Balloon Catheter-Mediated Transarterial Chemotherapy Delivery in a Swine Model: A Mechanism Recruiting the Vasa Vasorum for Localized Therapies
This report examines the potential mechanism of localized drug delivery via trans-arterial micro perfusion (TAMP) using a proprietary adjustable double-balloon occlusion catheter in a porcine model. Adult Yorkshire swine (N=21) were used in IACUC-approved protocols. The RC-120 catheter was positioned into visceral, femoral, and pulmonary arteries with infusion of methylene blue dye, gemcitabine, or gold nanoparticles.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Khashayar Farsad, Paula M. Novelli, Christopher Laing, Ripal T. Gandhi, Jacob Cynamon, Claudia S. L ópez, Erin S. Stempinski, Robert Strasser, Ramtin Agah Tags: Laboratory Investigation Source Type: research
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