Association of maternal blood high-mobility group box 1 levels and adverse pregnancy outcomes: A systematic review and meta-analysis

In conclusion, overexpressed maternal blood HMGB1 levels were associated with adverse pregnancy outcomes, including PE, GDM and URSA. Further studies should be conducted to validate the efficacy of HMGB1 as a biomarker for assessing the risk of adverse pregnancy outcomes.PMID:38492434 | DOI:10.1016/j.repbio.2024.100859

Source: Reproductive Biology - March 16, 2024 Category: Reproduction Medicine Authors: Liping Xue Ruolin Chen Ying Liu Peiguang Niu Jintuo Zhou Jinhua Liu Jinhua Zhang Huajiao Chen Source Type: research