Impact of pharmacogenomic profiles on post-surgical pain following laparotomy for gynecologic pathology

CONCLUSIONS: A positive association existed between increased CYP2D6 activity and in-hospital opioid requirements, especially in the first 24 h after surgery. This provides important information to further individualize opioid prescriptions for patients undergoing laparotomy for gynecologic pathology.PMID:38479169 | DOI:10.1016/j.ygyno.2024.03.001

Source: Gynecologic Oncology - March 13, 2024 Category: Cancer & Oncology Authors: Gretchen E Glaser Brandon Maddy Amanika Kumar Karen Ishitani Maureen A Lemens Kristine Hanson Ann M Moyer Elizabeth Habermann Sean C Dowdy Source Type: research