Effects of Calorie Restriction on Preserving Male Fertility Particularly in a State of Obesity

AbstractPurpose of ReviewHighlight the importance of exploring nutritional interventions that could be applied as alternative or supplementary therapeutic strategies to enhance men ’s fertility.Recent FindingsLifestyle choices have  prompted extensive discussions regarding its implications and applications as a complementary therapy. The growing concern over the decline in sperm quality underscores the urgency of investigating these alternative interventions. Calorie restriction (CR) has emerged as a promising strategy to imp rove male fertility. While the efficacy of CR depends on factors like age, ethnicity, and genetics, observational studies and clinical trials, such as CALERIE, have shown an improvement in serum testosterone level and sexual drive in men with or without obesity. Additionally, in a case-control stu dy, a high intake of saturated and trans-fatty acids improved sperm motility in asthenozoospermic men. Vast data demonstrate that CR positively impacts sperm count and motility; however, its effects on sperm morphology and DNA fragmentation remain less clear, and the literature has shown discrepanci es, mainly due to the nature of technical-dependent assessment tools.SummaryThe review advocates a personalized approach to CR, considering individual health profiles to maximize its benefits. It underscores the need for routine, accessible diagnostic techniques in male reproductive health. It  suggests that future research should focus on personalized dietary...
Source: Current Obesity Reports - Category: Eating Disorders & Weight Management Source Type: research