High-performance presurgical differentiation of glioblastoma and metastasis by means of multiparametric neurite orientation dispersion and density imaging (NODDI) radiomics

ConclusionThe NODDI radiomics model showed promising performance for preoperative discrimination between Gb and SBM.Clinical relevance statementThe NODDI radiomics model showed promising performance for preoperative discrimination between Gb and SBM, and radiomics features can be incorporated into the multidimensional phenotypic features that describe tumor heterogeneity.Key Points•The neurite orientation dispersion and density imaging (NODDI) radiomics model showed promising performance for preoperative discrimination between glioblastoma and solitary brain metastasis.•Compared with other tumor volumes of interest, the NODDI radiomics model based on solid tumor regions performed best in distinguishing the two types of tumors.•The performance of the single-parameter NODDI model was inferior to that of the combined-parameter NODDI model.
Source: European Radiology - Category: Radiology Source Type: research