A novel method for simultaneous detection of hematological tumors and infectious pathogens by metagenomic next generation sequencing of plasma

CONCLUSIONS: Concurrent CNV analysis alongside mNGS for infection diagnosis is promising for detecting malignant tumors. We recommend adopting a CNV region of 10Mbp over 5Mbp for our model, because of the lower false-positive rate (FPR).PMID:38484907 | DOI:10.1016/j.cca.2024.117874
Source: International Journal of Clinical Chemistry - Category: Chemistry Authors: Source Type: research