Initial Experience of Proton-Based Stereotactic Body Radiotherapy for Head and Neck Reirradiation

Up to 50% of patients with head and neck cancer (HNC) may recur after initial treatment, which often includes a combination of surgery, chemotherapy, and radiation. Reirradiation is an effective treatment option with high rates of local control. Hypofractionated regimens may be desirable due to high biologically effective doses, however they can be complicated by high rates of toxicity. Intensity-modulated proton therapy (IMPT) plans have dosimetric advantages compared to standard photon plans. We sought to review initial patient tolerance and treatment outcomes of proton-based stereotactic body radiotherapy (SBRT) for reirradiation of HNC.

Source: International Journal of Radiation Oncology * Biology * Physics - March 14, 2024 Category: Radiology Authors: N. Ali, D. Bohannon, J. Zhou, M.W. McDonald, W.A. Stokes, S. Rudra, J.S. Remick, S. Tian, J.E. Bates Tags: 146 Source Type: research