Survival Outcomes following Pulmonary Metastasis-Directed Local Therapy (PM-LT) Relative to No Metastasis-Directed Intervention in Adenoid Cystic Carcinoma (ACC)
ACC has a high rate of recurrence and distant metastasis (DM), despite aggressive curative-intent primary therapy. The lung is the most common site of DM, most often with indolent disease growth. Given the lack of FDA-approved systemic therapy for metastatic ACC, PM-LT is frequently used. The survival impact of PM-LT is not known and there is no consensus on whether routine PM-LT is appropriate. The purpose of this study was to assess the survival outcomes of ACC patients (pts) who underwent PM-LT and compare to those who did not.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: C.O. Hoff, L. Feng, F. Bonini, L.G. Sousa, K. Wang, J.M. Siqueira, A. Purushothaman, Q.N. Nguyen, A.K. El-Naggar, R. Mehran, R. Ferrarotto Tags: 242 Source Type: research