Structure-based approaches for the design of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d][1,2,3]triazoles as tubulin polymerization inhibitors

In conclusion, this report shows a successful case of the structure-based design approach of a potent tubulin polymerization inhibitor for cancer treatment.PMID:38471357 | DOI:10.1016/j.ejmech.2024.116309

Source: European Journal of Medicinal Chemistry - March 12, 2024 Category: Chemistry Authors: Mingxin Huang Hongyao Han Haoyuan Liu Runlai Liu Jiwei Li Mi Li Qi Guan Weige Zhang Dun Wang Source Type: research