Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-na ïve celiac disease

CONCLUSIONS: Our data suggests that ISC niche failure is a plausible hypothesis for villous flattening in patients with CeD, resulting from pericrypt IgA anti-TG2 antibody complex-mediated stromal depletion.PMID:38427764 | DOI:10.4103/ijpm.ijpm_760_23

Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Prasenjit Das Sudha Battu Lalita Mehra Alka Singh Muzaffar Ahmad Ashish Agarwal Ashish Chauhan Anam Ahmad Sreenivas Vishnubhatla Siddhartha Datta Gupta Vineet Ahuja Govind Makharia Source Type: research