Pubertal exposure to Microcystin-LR arrests spermatogonia proliferation by inducing DSB and inhibiting SIRT6 dependent DNA repair in vivo and in vitro

This study reports the effect of pubertal exposure to MC-LR on spermatogenesis and complex mechanism how MC-LR induces spermatogonia cell proliferation inhibition.PMID:38460408 | DOI:10.1016/j.ecoenv.2024.116191

Source: Ecotoxicology and Environmental Safety - March 9, 2024 Category: Environmental Health Authors: Yu-Lin Liu Jia-Yu Liu Xin-Xin Zhu Jian-Hua Wei Shuang-Ling Mi Su-Ya Liu Xiu-Liang Li Wei-Wei Zhang Ling-Li Zhao Hua Wang De-Xiang Xu Lan Gao Source Type: research