Primary pure large cell neuroendocrine carcinoma of the urinary bladder: a case report and literature review

ConclusionsWe reviewed domestic and foreign literature and found no explicit treatment protocols exist for the disease. Surgical resection combined with chemotherapy were the most common treatments. Herein, we reported the first case of primary, pure LCNEC of the urinary bladder treated by radical cystectomy combined with pure immunotherapy, achieving sustained remission, which provides a new idea for the immunotherapy and integrative treatment of the disease.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research