Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes

In this study, using mass spectrometry and Western blotting, we detected expression of DRAXIN in a medium of A549 cells exposed to A + N. Thus, this protein functions not only in the development of the nervous system, but it may also have a new cancer-related function.PMID:38460933 | DOI:10.1016/j.cbi.2024.110946

Source: Chemico-Biological Interactions - March 9, 2024 Category: Molecular Biology Authors: Barbara Łasut-Szyszka Agnieszka Gdowicz-K łosok Beata Ma łachowska Ma łgorzata Krześniak Agnieszka B ędzińska Marta Gawin Monika Pietrowska Marek Rusin Source Type: research