Targeting cell surface glucose-regulated protein 94 in gastric cancer with an anti-GRP94 human monoclonal antibody

In conclusion, our study suggests that cell surface GRP94 may be a potential therapeutic target in GC, and that antibody-based targeting of cell surface GRP94 may be an effective strategy for inhibiting GRP94-mediated GC growth and angiogenesis.PMID:38449302

Source: BMB Reports - March 7, 2024 Category: Biochemistry Authors: Hyun Jung Kim Yea Bin Cho Kyun Heo Ji Woong Kim Ha Gyeong Shin Eun-Bi Lee Seong-Min Park Jong Bae Park Sukmook Lee Source Type: research