Nesprin1 deficiency is associated with poor prognosis of renal cell carcinoma and resistance to sunitinib treatment

CONCLUSIONS: The results indicate that the expression of SYNE1/Nesprin1 and SYNE1 mutations in patients with RCC are closely linked to their prognosis and responsiveness to sunitinib treatment.PMID:38442705 | DOI:10.1159/000536539

Source: Oncology - March 5, 2024 Category: Cancer & Oncology Authors: Takafumi Fukushima Kohei Kobatake Kento Miura Kenshiro Takemoto Ryoken Yamanaka Ryo Tasaka Yuki Kohada Shunsuke Miyamoto Yohei Sekino Hiroyuki Kitano Keisuke Goto Kenichiro Ikeda Akihiro Goriki Keisuke Hieda Osamu Kaminuma Nobuyuki Hinata Source Type: research