Phthalate metabolites and sex steroid hormones in relation to obesity in US adults: NHANES 2013-2016

ConclusionsIndividuals with obesity exhibit lower levels of TT and SHBG, accompanied by elevated estradiol levels. Exposure to PAEs disrupts sex hormone levels, contributing to an increased risk of obesity in US adults. In the exploration of the interrelationships among these three factors, the RF and XGBoost algorithm models demonstrated superior performance, with sex hormones displaying higher variable importance.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research