Sex-Based Differences in Opioid Administration: A Puzzle Yet to Be Solved

We read with great interest the paper published by Karamesinis et al. comparing sex-based differences in opioid administration after cardiac surgery.1 The authors concluded that female sex was associated with a significantly lower amount of opioid administration. Although the authors did a commendable job of accounting for many potential covariates, ongoing concerns about sex disparities in pain management and the complex nature of pain warrant a close examination of the results presented in the manuscript.

Source: Journal of Cardiothoracic and Vascular Anesthesia - February 21, 2024 Category: Anesthesiology Authors: Aimee Pak, Hannah Smith, Hisako Okada, Amir L. Butt Tags: Letter to the Editor Source Type: research