Characterizing of intra-amniotic inflammatory changes associated with chronic inflammation in the placenta marked by elevated amniotic fluid interferon gamma-induced protein 10 (IP-10) in pregnancies complicated by preterm prelabor rupture of membranes

Preterm delivery (PTD), which refers to delivery occurring before 37  weeks of gestation, is a significant contributor to perinatal mortality and morbidity, as extensively supported by research studies [1,2]. The World Health Organization estimates that approximately 13.4 million children worldwide are born preterm [2,3]. The incidence of PTD in developed countries ranges from 5 % to 12 % [2,4,5]. Preterm prelabor rupture of membranes (PPROM) represents a clinical phenotype of spontaneous PTD, characterized by the rupture of the fetal membranes prior to the onset of labor and before 37 weeks of gestation.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research