Disentangling the neurobiological bases of temporal impulsivity in Huntington's disease

ConclusionsThe present findings highlight the importance of investigating the spectrum of temporal impulsivity in HD. As, while less prevalent than other psychiatric features, this symptom is still reported to significantly impact the quality of life of patients and caregivers. This study provides evidence that individual differences observed in temporal impulsivity may be explained by variability in limbic frontostriatal tracts, while shedding light on the role of sensitivity to reward in modulating impulsive behavior through the selection of immediate rewards.

Source: Brain and Behavior - March 7, 2024 Category: Neurology Authors: Helena Pardina ‐Torner, Audrey E. De Paepe, Clara Garcia‐Gorro, Nadia Rodriguez‐Dechicha, Irene Vaquer, Matilde Calopa, Jesus Ruiz‐Idiago, Celia Mareca, Ruth de Diego‐Balaguer, Estela Camara Tags: ORIGINAL ARTICLE Source Type: research