Monocyte-to-high-density lipoprotein ratio is associated with systemic inflammation, insulin resistance and coronary subclinical atherosclerosis in psoriasis: results from 2 observational cohorts
Systemic inflammation or insulin resistance drive atherosclerosis. However, they are difficult to capture for assessing cardiovascular risk in clinical settings. The monocyte-to-HDL ratio (MHR) is an accessible biomarker that integrates inflammatory and metabolic information and which has been associated with poorer cardiovascular outcomes. Our aim was to evaluate the association of MHR with the presence of subclinical atherosclerosis in patients with psoriasis. The study involved a European and an American cohort including 405 patients with the disease.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Emilio Berna-Rico, Carlota Abbad-Jaime de Aragon, Asuncion Ballester-Martinez, Javier Perez-Bootello, Jorge Solis, Leticia Fernandez-Friera, Mar Llamas-Velasco, Maria Castellanos-Gonzalez, Maria G. Barderas, Carlos Azcarraga-Llobet, Emilio Garcia-Mouronte Tags: Original Article Source Type: research