Comprehensive study of chromosomal CNVs and genomic variations predicting overall survival in Myelodysplastic syndromes

CONCLUSION: CGH + SNP array changed the cytogenetic and IPSS-R risk group in 18% and 13% of patients respectively with an improved prediction of prognosis. This study emphasizes the cytogenetic heterogeneity of MDS and highlights that abnormality with chromosome 2 may have a diagnostic and prognostic impact.PMID:38442690 | DOI:10.1159/000536446

Source: Oncology - March 5, 2024 Category: Cancer & Oncology Authors: Nehakumari Maurya Chandrakala Shanmukhaiah Somprakash Dhangar Manisha Madkaikar Babu Rao Vundinti Source Type: research