Polysomnographic features associated with clonazepam and melatonin treatment in isolated REM sleep behavior disorder: Time for new therapeutic approaches?

CONCLUSION: These results suggest that the administration of MLT or CLO impacts (positively) on sleep parameters of iRBD patients. However, there is a need to better stratify patients, in order to treat them in a targeted manner, depending on the patient's individual sleep architecture and expected differential effects of these agents.PMID:38421131 | DOI:10.1111/cns.14569

Source: CNS Neuroscience and Therapeutics - February 29, 2024 Category: Neuroscience Authors: Maria P Mogavero Raffaele Ferri Sara Marelli Giuseppe Lanza Michele Terzaghi Alessandra Castelnuovo Lourdes M DelRosso Carlos H Schenck Luigi Ferini-Strambi Source Type: research