Cefazolin vs cloxacillin in MSSA endocarditis: too good to be true?

With great interest, I read the article by Herrera-Hidalgo et al. on cefazolin versus cloxacillin for methicillin-susceptible Staphylococcus aureus (MSSA) endocarditis [1]. This topic is relevant for clinical practice because MSSA endocarditis is difficult to treat and new studies comparing treatment strategies are urgently needed. However, I have a few concerns regarding the methodological and statistical approach used and their consequences for the conclusions reached.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research