Epigenome-Wide Association Studies of COPD and Lung Function: A Systematic Review

CONCLUSIONS: There is high heterogeneity across published COPD/lung function EWAS studies. A few genes (n=123; 2.6%) were replicated in blood and respiratory samples, suggesting that blood can recapitulate some changes in respiratory tissues. These findings have implications for future research.PMID:38422471 | DOI:10.1164/rccm.202302-0231OC

Source: Am J Respir Crit Car... - February 29, 2024 Category: Intensive Care Authors: Sandra Casas-Recasens Raisa Cassim N úria Mendoza Alvar Agusti Caroline Lodge Shuai Li Dinh Bui David Martino Shyamali C Dharmage Rosa Faner Source Type: research