Investigation of the risk factors in the development of radionecrosis in patients with brain metastases undergoing stereotactic radiotherapy

CONCLUSIONS: SRT is used effectively in BMs. The incidence of RN following SRT is undeniably frequent. It was observed that the incidence rate increased as the follow-up period increased. We showed that brain-GTV doses are not predictive of RN development, unlike other publications. In study, a high SIR score and supratentorial localization were identified as factors that increased the risk of radionecrosis.ADVANCES IN KNOWLEDGE: RN is still a common complication after SRT. Symptomatic RN is a significant cause of morbidity. The causes of RN are still not clearly identified. In many publications, brain dose and volumes have been found to be effective in RN. But, with this study, we found that brain dose volumes and fractionation did not increase the incidence of RN when brain doses were taken into account. The most important factor in the development of RN was found to be related to long survival after SRT.PMID:38426391 | DOI:10.1093/bjr/tqae051
Source: The British Journal of Radiology - Category: Radiology Authors: Source Type: research