Signatures of migraine aura in high-density-EEG

CONCLUSIONS: Unequivocal signatures of spreading depolarization were not recorded with EEG on the intact scalp in migraine. The decrease in alpha-power contralateral to predominant visual symptoms is consistent with focal depression of spontaneous brain activity as a consequence of cortical spreading depolarization but is not specific thereof.SIGNIFICANCE: Cortical spreading depolarization is relevant in migraine, other paroxysmal neurological disorders and neurointensive care.PMID:38422969 | DOI:10.1016/j.clinph.2024.01.008

Source: Clinical Neurophysiology - February 29, 2024 Category: Neurology Authors: Franz Riederer Johannes Beiersdorf Clemens Lang Agnes Pirker-Kees Antonia Klein Adrian Scutelnic Kirsten Platho-Elwischger Christoph Baumgartner Jens P Dreier Christoph Schankin Source Type: research