Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice
In conclusion, our preclinical data support that S. amarissima possesses anticonvulsant properties, in part due to the presence of amarisolide A, mediated by different inhibitory mechanisms of action. Our scientific evidence suggests that this Salvia species and amarisolide A are potential neuroprotective alternatives to control seizures in epilepsy therapy.PMID:38417289 | DOI:10.1016/j.biopha.2024.116352
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Rodrigo Mendoza-Madrigal Mar ía Eva González-Trujano Daniela Onofre-Campos Gabriel Fernando Moreno-P érez Jazmin Guadalupe Castellanos-Mijangos David Mart ínez-Vargas Source Type: research
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