Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages

This study validates drug repurposing as a strategy for the identification of novel anti-inflammatory medicines and highlights sunitinib as a potential drug repurposing candidate for inflammatory disease via inhibition of NF-κB signalling.PMID:38417608 | DOI:10.1016/j.ejphar.2024.176437

Source: European Journal of Pharmacology - February 28, 2024 Category: Drugs & Pharmacology Authors: Laura E Chaffey Annabell Roberti Amelia Bowman Conan Jo O'Brien Liliana Som Gareth Sd Purvis David R Greaves Source Type: research