Improvement by Medication Less than Expected in Parkinson's Disease: Blinded Evaluation of Levodopa Response

CONCLUSIONS: We showed an acute effect of levodopa using LDCT that was around 30% improvement. While it lends support to the use of this limit in the MDS diagnostic criteria, an acute effect of less than 30% should be considered acceptable in some patients. Our study highlights a discrepancy in the objective measure of medicine effect on motor symptoms and the patient's subjective evaluation.PMID:38419645 | PMC:PMC10901577 | DOI:10.1155/2024/2649578

Source: Parkinsons Disease - February 29, 2024 Category: Neurology Authors: Mette Niemann Johansen Anna Handberg Mohamed El Haddouchi Josefine Grundtvig Steen Rusborg Jensen Lisette Salvesen Annemette L økkegaard Source Type: research