Diosgenyl glucosamine conjugates increase pro-apoptotic and selective activities in cancer cell lines

CONCLUSIONS: Altogether, these results demonstrate that diosgenin glucosamine compounds exert an antiproliferative effect on cancer cell lines and induce apoptotic effects more efficiently than diosgenin alone without affecting non-tumour cells.SIGNIFICANCE: This study evidences the pro-apoptotic and selective activities of diosgenyl glucosamine compounds in cancer cell lines.PMID:38408271 | DOI:10.1111/boc.202300052

Source: Biology of the Cell - February 26, 2024 Category: Cytology Authors: Mart ínez Mata Sergio Iván Escobar S ánchez María Luisa L ópez Muñoz Hugo Hilario Mart ínez Jazmín Ciciolil Sandoval Ram írez Jesús Aparicio S ánchez Uriel Yair S ánchez Sánchez Luis Source Type: research