Pathogenic Variant Intraductal Papillary Mucinous Neoplasms Tumors Show Increased Tumor Growth Compared With Those With Familial Pancreatic Cancer Kindreds: Prognostic Indicators

We read with much interest the recent extensive study by Overbeek et  al1 of the Dutch Familial Pancreatic Cancer Surveillance Study working group in which they define the incidence, growth rate, and risk of pancreatic malignancy in patients with pathogenic variants compared with pancreatic cancer kindreds. They pointed out that a limitation of their study was the l ack of determining IPMN histology, which they ascribed to “common clinical practice.” We agree with this study limitation but note that this limitation may have missed an opportunity to establish accurate histologic diagnosis and better tumor prognostication.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Letters to the Editor Source Type: research