Association of Y chromosome AZF region microdeletions with recurrent miscarriage in Iranian couples: A case-control study
CONCLUSION: Microdeletions in sY134 (AZFb) were significantly associated with RPL in Iranian men (p = 0.03). AZF microdeletion screening in couples with RPL can provide valuable information for ethnical genetic counseling and management of recurrent miscarriage. Further studies on larger populations or across various ethnic groups, conclusions and the inclusion of other factors like epigenetic changes explain the role of AZF microdeletions in RPL.PMID:38407572 | DOI:10.1002/mgg3.2392
Source: Molecular Medicine - Category: Molecular Biology Authors: Nasrin Pazoki Mitra Salehi Seyed Abdolhamid Angaji Meghdad Abdollahpour-Alitappeh Source Type: research
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