MicroRNA-320a enhances LRWD1 expression through the AGO2/FXR1-dependent pathway to affect cell behaviors and the oxidative stress response in human testicular embryonic carcinoma cells

CONCLUSIONS: This is the first study showing the role of miR-320a in upregulating the testicular cancer-specific regulator LRWD1 and the importance of the AGO2/FXR1 complex in miR-320a-mediated upregulation of LRWD1 during testicular cancer progression.PMID:38385979 | DOI:10.18632/aging.205571

Source: Aging - February 22, 2024 Category: Biomedical Science Authors: Yi-Hsiung Lin Chia-Hui Su Hsin-Mei Chen Ming-Syuan Wu Hsien-An Pan Chia-Ning Chang Yu-Sheng Cheng Wen-Tsan Chang Chien-Chih Chiu Yen-Ni Teng Source Type: research