Polyene phosphatidylcholine enhances the therapeutic response of oxaliplatin in gastric cancer through Nrf2/HMOX1 mediated ferroptosis

In conclusion, our study reveals the synergistic antitumour potential of PPC and OXA while protecting patients against hepatic injury. This suggests a promising combined treatment approach for patients with advanced gastric cancer.PMID:38377934 | DOI:10.1016/j.tranon.2024.101911

Source: Translational Oncology - February 20, 2024 Category: Cancer & Oncology Authors: Peijie Lei Lianjing Cao Hongjun Zhang Jialei Fu Xiaojuan Wei Fei Zhou Jingjing Cheng Jie Ming Haijun Lu Tao Jiang Source Type: research