Inhibitory Effects of Tricyclic Antidepressants on Human Liver Microsomal Morphine Glucuronidation: Application of IVIVE to Predict Potential Drug-Drug Interactions in Humans

CONCLUSION: The results suggest that the likelihood of potential clinical DDIs arising from tricyclic antidepressant inhibition on morphine glucuronidation is low.PMID:38270153 | DOI:10.2174/0113892002270594231212090958

Source: Current Drug Metabolism - January 25, 2024 Category: Drugs & Pharmacology Authors: Verawan Uchaipichat Source Type: research