The Role of NAD+ in Myocardial Ischemia-induced Heart Failure in Sprague-Dawley Rats and Beagles

CONCLUSION: The ratios of heart weight indexes, fibrotic areas, and MI rates in the CZ696 and medium and high NAD+ dose groups were lower than those in the HF group. Medium and high-dose NAD+ showed superior positive effects on myocardial hypertrophy, cardiac function, and myocardial fibrosis and reduced the MI rate.PMID:38357951 | DOI:10.2174/0113892010275059240103054554

Source: Current Pharmaceutical Biotechnology - February 15, 2024 Category: Biotechnology Authors: Zuowei Pei Chenguang Yang Ying Guo Min Dong Fang Wang Source Type: research