Histamine- and Pruritogen-induced Itch is Inhibited by a TRPM8 Agonist in Humans: A Randomized, Vehicle-controlled Trial

CONCLUSIONS: The study demonstrates that the specific TRPM8 agonist gel effectively suppresses human skin itch induced by various pruritogens. These versatile actions suggest cooling agents may be promising treatments for multiple forms of itch stimuli.PMID:38345103 | DOI:10.1093/bjd/ljae054

Source: The British Journal of Dermatology - February 12, 2024 Category: Dermatology Authors: Soyeon Lee Edward T Wei Tudor Selescu Alexandru Babes Jinseo Park Jincheol Kim Boyoung Chung Chunwook Park Hyeone Kim Source Type: research